Search results for “high-throughput”

About 8 results in articles

Open Access Pub publishes peer-reviewed, free-to-read open-access articles. Showing articles matching high-throughput — open any to read the full text, or download the PDF or XML.

High-Throughput Complex Disease Modeling for Ethical Drug Discovery: Clinical Relevance of a NAM Platform for Cancer Biomarker Development

May 2026 DOI 10.14302/issn.2572-3030.jcgb-26-6307
Arne-C. FaisstCorresponding author

The development of tumor biomarkers derived from blood, or its components, has become pivotal in advancing early cancer diagnosis. Malignant transformations induce cancer-specific alterations in the transcriptome, proteome, and secretome of tumor cells. Recent studies highlighted similar alterations…

Ovarian Cancer Identification Based on Feature Weighting for High-Throughput Mass Spectrometry Data

Mar 2018
Xiaoping LiuCorresponding author

An important use of proteomics data from Mass Spectrometry (MS) is the classification of tumor types with respect to peptides in specific cancer types. It is highly critical to find an optimal set of markers among specific cancer peptides whose expression can be clinically utilized to build assays f…

Identification of Antioxidant Activity of Medicinal Plant Extracts Through a Modified and Rapid ABTS Colorimetric Assay

Nov 2026 DOI 10.14302/issn.2471-2140.jaa-26-6462
Anthony L. NewsomeCorresponding author

The consumption of antioxidant rich plants is a common human activity. Therefore, easily used, time efficient and effective antioxidant assays of plants consumed by humans are of increasing importance. The ABTS [2,2’-azinobis-(3-ethtlbenzothiazoline-6-sulfonic acid)] cation radical is commonly used…

Proteomic and Genomic Techniques in Medical Research: Applications in Cancer, Diagnostics, and Personalized Medicine

Nov 2025 DOI 10.14302/issn.2326-0793.jpgr-25-5573
Oghenetega E. ImiruayeCorresponding author

Advancements in proteomic and genomic technologies have transformed molecular biology by enabling comprehensive analysis of biological systems at the molecular level. This literature review explores the evolution, methodologies, and practical applications of key proteomic and genomic techniques. In…

Molecular Diagnosis in Clinical Management and Diagnosis of Thyroid Cancer

Jan 2024 DOI 10.14302/issn.2574-4496.jtc-23-4835
Abbas Hussein Saleh HusseinCorresponding author

The prevalence of thyroid cancer is rapidly increasing worldwide, majorly due to overdiagnosis and overtreatment methods of differentiated thyroid cancer. The emergent and potent preclinical models, high-throughput molecular techniques, and genetic expression microarrays have delivered deeper insigh…

The Current Immunoassays and Emerging Immunogenomic Approaches for Immunomonitoring Cancer and Infectious Diseases

Jan 2019 DOI 10.14302/issn.2572-3030.jcgb-18-2527
Xi ZhangCorresponding author

As remarkable advances have been made in immunotherapies, the overall goal of immunotherapy has become the selection of patients and evaluating the benefits of treatment. One of the major obstacles to develop immunotherapies is the lack of effective immune monitoring. Monitoring of key changes in th…

Comparison of an HPLC-MS/MS Method with Multiple Commercial ELISA Kits on the Determination of Levels of 8-oxo-7,8-Dihydro-2'-Deoxyguanosine in Human Urine

Dec 2018 DOI 10.14302/issn.2377-2549.jndc-18-2430
John P. Richie JrCorresponding author

Introduction: Analysis of 8-oxodG is usually conducted by either chromatography-based methods or by immunochemical methods commonly used based upon their low cost and high-throughput. However, concern regarding the accuracy of ELISA methods has complicated their use. We directly compare the levels o…

The Development and Evaluation of A Multiplex Real-Time PCR Assay for the Detection of ESBL Genes in Urinary Tract Infections

Aug 2018 DOI 10.14302/issn.2690-4721.ijcm-18-2217
Shivanthi SamarasCorresponding author

Background Overuse of beta-lactam antibiotics has lead to selection for extended-spectrum β-lactamase (ESBL) producing Enterobacteriaceae, a major cause of antibiotic resistant urinary tract infections (UTIs). Standard detection methods are time-consuming, with disputed accuracy. This study describe…

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