Search results for “PAM”

About 19 results in articles

Open Access Pub publishes peer-reviewed, free-to-read open-access articles. Showing articles matching PAM — open any to read the full text, or download the PDF or XML.

Investigating the Effect of Dopamine on in Vitro Maturation, Fertilization and Development of Immature Bovine Oocytes

Mar 2024 DOI 10.14302/issn.2575-1212.jvhc-24-4888
Mohammed A ElmetwallyCorresponding author

Proteins and other nitrogenous substances such as polyamines, catecholamines, and nitric oxide require amino acids for synthesis. The purpose of this study was to see how adding dopamine to either maturation or fertilization medium affected the developmental competence of immature bovine oocytes. In…

Concomitant in Vivo Voltammetric and Electrophysiological Analysis Indicate that Nociceptin/Orphanin FQ Affects Dopamine and then Serotonin Activities in Brain Substancia Nigra.

Apr 2019 DOI 10.14302/issn.2578-8590.ipj-19-2772
Francesco CrespiCorresponding author

Nociceptin/orphanin-FQ (NOCI) together with its receptor NOP are widely expressed in cortical and subcortical motor areas and it is known that NOCI acts as an anxiolytic attenuating the behavioral inhibition of animals acutely exposed to stressful/anxiogenic conditions. Influence of NOCI upon the do…

Evaluating the Efficacy of Gene Silencing in Dopaminergic Neuronal Cells In-Vitro using Gold Nanorods (GNR) with Different Surface Properties Complexed to DARPP-32 siRNA.

Jan 2014 DOI 10.14302/issn.2328-0182.japst-12-183
Supriya D. MahajanCorresponding author

Gold nanorods (GNRs) are plasmonic nanostructures by virtue of their size-dependent optical properties, offer a bionanotechnology platform in areas of bioimaging, drug delivery etc for disease diagnosis, prognosis, and therapy. GNRs are more sensitive to changes in local environments, and offer stro…

Apomorphine Subcutaneous Infusion is More Efficient Than foslevodopa/foscarbidopa Subcutaneous Infusion in the Treatment of Advanced Parkison´s Disease for the Spanish National Health System

May 2026 DOI 10.14302/issn.2641-4538.jphi-26-6161
J GonzalezCorresponding author

Objectives Motor fluctuations and non-motor disorders not manageable by first-line treatments in advanced Parkinson's disease require continuous dopaminergic stimulation strategies such as subcutaneous infusions of apomorphine (APO) or foslevodopa/foscarbidopa (FLD/FCD). A Budget Impact Analysis (BI…

Cervical Cancer with The Active And Stable PI3K/MTOR/AKT Pathway In Azerbaijan Patients

Mar 2024 DOI 10.14302/issn.2997-2108.jcc-23-4838
Konul S. MardanovaCorresponding author

Among the reproductive cancers cervical cancer has special place, because the second most frequent cause of cancer-related death among women worldwide. The studies suggested that the PI3K/mTOR/AKT signaling pathway is associated with certain reproductive tumors. A lot of research is ongoing for unde…

Clustering objects for spatial data mining: a comparative study

Mar 2023 DOI 10.14302/issn.2768-0207.jbr-23-4478
Youssef FAKIRCorresponding author

Spatial data mining (SDM) is searching important relationships and characteristics that can clearly exist in spatial databases. This content aims to compare object clustering algorithms for spatial data mining, before identifying the most efficient algorithm. To this end, this paper compare k-means,…

The Effect of Food Intakes on Musculoskeletal Pains

Aug 2020 DOI 10.14302/issn.2832-4048.jsm-20-3519
Seyedeh Nasim HabibzadehCorresponding author

Some certain foods or drinks have specific effects on musculoskeletal frameworks in time of pain. For instance, the extra intake of salt declines muscular spams (or cramps) in different limbs. The regular consumptions of milk products reduce the upper or lower musculature weakness and pain. The hot…

Caffeine Components Empower the Brain Potentiality

Aug 2020 DOI 10.14302/issn.2694-1201.jsn-20-3523
Seyedeh Nasim HabibzadehCorresponding author

The brain requires certain fuels to function in high level. Literally, nutritional components can modulate the brain productivity. One of the right nutrition to enhance the brain power is dietary component of caffeine. Caffeine as a component of coffee, tea and chocolate is very popular. Although, d…

Molecular Analysis of 6-pyruvoyltetrahydropterin Synthase Gene in Atypical Phenylketonuric Egyptian Patients

Jul 2020 DOI 10.14302/issn.2576-6694.jbbs-20-3450
Magdy M. MahmoudCorresponding author

Background Hyperphenylalaninemia (HPA) combined with neurological signs due to impaired catecholamine, dopamine and serotonin synthesis. Symptoms may appears in first week of life but most seen in age of 4 months. Atypical PKU disease caused mainly by deficiency in 6-pyruvoyltetrahydropterin synthas…

A Meningeal Syndrome Revealing A Tetanus in A Togolese: Case Report and Review of the Literature

Aug 2019 DOI 10.14302/issn.2470-5020.jnrt-19-2983
Léhleng AGBACorresponding author Neurology Department, University Hospital Center of Kara, Kara University, PoBox 18 Kara (Togo)

Although it is a vaccine-preventable disease, tetanus is frequently found in sub-Saharan Africa. Because of its rarity, this disease poses two problems for doctors of the 21st century: to make early diagnosis in order to refer patients to appropriate care structures, and to continue to ensure correc…

Isolation of Human Monoclonal scfv Antibody Specifically Recognizing the D2-5-Ht1a Heteromer.

Apr 2019 DOI 10.14302/issn.2377-2549.jndc-19-2736
Sylwia ŁukasiewiczCorresponding author

Antibody phage display has become a useful technique for discovering and optimizing target-specific monoclonal antibodies suitable for many applications, including therapeutic ligands, which may act as direct pharmacological compounds or may be used as targeting ligands for controlled drug delivery.…

Application of Acrylates in Enhanced Oil Recovery

Apr 2019 DOI 10.14302/issn.2377-2549.jndc-19-2720
A.N. El-hoshoudyCorresponding author

Currently, enhanced oil recovery (EOR) acquire increased attention to recover more residual oil trapped after the primary and secondary process in petroleum reservoirs. EOR comprise different technologies involving chemical, thermal, miscible flooding techniques. Chemical flooding by the polymer is…

A Rare Cause of Fever of Unknown Origin: Reverse Shapiro’s Syndrome

Mar 2019 DOI 10.14302/issn.2474-3585.jpmc-19-2655
Habip GedikCorresponding author

Reverse Shapiro’s syndrome is described as unexplained hyperthermia coexisting with agenesis of the corpus callosum. Its pathophysiology dwells on the role of dopaminergic hypersensitivity caused by hypothalamic dysfunction. Until now, only 5 cases have been described in the literature as reverse Sh…

Resolution of Fetal Hydrops in a Case of Congenital Pulmonary Airway Malformation

Nov 2018 DOI 10.14302/issn.2997-2086.jfs-18-2245
Katharine ClarizioCorresponding author

Congenital pulmonary airway malformation (CPAM) can often be noted on fetal ultrasound. When a CPAM is noted in the face of fetal hydrops, the outcome is dismal. Surgical interventions and administration of antenatal steroids can be considered for treatment, but in hydropic fetuses these interventio…

Bacterial Meningitis Associated with Pituitary Macroadenoma: Systematic Review

May 2017 DOI 10.14302/issn.2470-5020.jnrt-17-1503
Moussa TOUDOU DAOUDACorresponding author

Introduction Bacterial meningitis complicates rarely pituitary macroadenomas. The aim of our systematic review is to study the features of the association between bacterial meningitis and pituitary macroadenoma. Methods We conducted a literature search in both MedLine and Google Scholar database fro…

Prevalence of Impulse Control Disorders among Adult Filipino Patients with Idiopathic Parkinson’s Disease seen at Jose R. Reyes Memorial Medical Center

Oct 2016 DOI 10.14302/issn.2470-5020.jnrt-16-1240
Jan Kristoper P. de GuzmanCorresponding author

Background: Impulse Control Disorders (ICDs) are characterized as pathologicalbehavioral patterns of excess impulsivity which may result as part of the non-motor complications of Parkinson’s disease (PD). These significantly affect the patient’s overall quality of life and have impact on their care…

Central Retinal Vein Occlusion in Hepatocellular Carcinoma

May 2015 DOI 10.14302/issn.2470-0436.jos-14-527
Srinivasan SanjayCorresponding author

A 66 year old Chinese male with a medical history of hypertension, diabetes mellitus and hepatitis B carrier was diagnosed with hepatocellular carcinoma in 2009. He underwent treatment with selective internal radiation spheres and sorafenib, and multiple cycles of chemotherapeutic agents such as bev…

The Toxicity of Iodinated Radiographic Contrast Agents in the Clinical Practice

May 2015 DOI 10.14302/issn.2574-4488.jna-14-601
Michele AndreucciCorresponding author

Iodinated radiographic contrast agents (IRCA) are pharmaceutical agents used to improve the visibility of internal organs and structures in X-ray based imaging techniques. However, IRCA may have adverse unwanted effects, ranging from a mild inconvenience, such as itching, to a life-threatening emerg…

Evaluation of Recruitment Approaches for the HPTN 052 Clinical Trial of HIV Serodiscordant Couples in Rural Western Kenya

Feb 2014 DOI 10.14302/issn.2324-7339.jcrhap-13-211
D. GustCorresponding author

Recruitment of couples is important for study success. The multi-centered HPTN 052 clinical trial was designed to evaluate whether immediate versus delayed use of ART by HIV-infected individuals would reduce transmission of HIV to their HIV-uninfected partners. The objective of this study was to ret…

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