Search results for “Antiretroviral”

About 24 results in articles

Open Access Pub publishes peer-reviewed, free-to-read open-access articles. Showing articles matching Antiretroviral — open any to read the full text, or download the PDF or XML.

HIV-Associated Peripheral Neuropathy and Antiretroviral Therapy: A Prospective Study from a Tertiary Care Centre in South India

Dec 2025 DOI 10.14302/issn.2324-7339.jcrhap-25-5515
Anagha RaoCorresponding author

Background Peripheral neuropathy (PN) is a common and debilitating complication in people living with HIV (PLHIV). While HIV itself contributes to neuropathy, certain antiretroviral therapy (ART) drugs, particularly nucleoside reverse transcriptase inhibitors (NRTIs) such as stavudine (d4T) and zido…

Spirometric profile of people living with HIV on antiretroviral drugs in Abidjan

Jan 2024 DOI 10.14302/issn.2642-9241.jrd-23-4809
Kadiatou SamakeCorresponding author

Introduction People living with HIV (PLHIV) are susceptible to developing non- communicable chronic respiratory diseases. Our objective was to study the spirometric profile of this population. Material and methods This was a descriptive and analytical cross-sectional retro-prospective study conducte…

Human Immunodeficiency Virus Drug Resistance (HIVDR) and Baseline Characteristics among Antiretroviral Therapy (ART) experienced Children and Adolescents under the care of Chidamoyo Christian Hospital in Hurungwe, Zimbabwe

Dec 2023 DOI 10.14302/issn.2324-7339.jcrhap-23-4634
Alfred MakuraCorresponding author

Introduction Human Immunodeficiency Virus (HIV) remains a persistent global public health challenge. In 2020, approximately 37.9 million individuals were living with HIV globally, including 1.7 million children <15 years old, with a global HIV prevalence of 0.8% among adults. A larger portion of peo…

Structural Equation Modeling to Detect Predictors of CD4 Cell Count Change due to Long Term Antiretroviral Therapy Administered to HIV-Positive Adults at Felege Hiwot Teaching and Specialized Hospital, Bahir Dar, Ethiopia

Mar 2020 DOI 10.14302/issn.2641-4538.jphi-19-2610
Awoke Seyoum TegegneCorresponding author

Background The relationship between predictors and the variable of interest was estimated using a structural equation model which is used to predict latent variables. The main advantage of the SEM is the ability to estimate the direct and indirect pathways of the effect of the primary independent va…

Knowledge, Attitude and Practice of Healthcare Workers Towards Availability of Antiretroviral Pre-Exposure Prohylaxis in Nigeria

Dec 2018 DOI 10.14302/issn.2324-7339.jcrhap-18-2333
Abayomi Joseph AfeCorresponding author

Introduction: The introduction of preexposure prophylaxis (PrEP) against incident HIV infection has changed the epidemiology of disease as continuous treatment with tenofovir and emtricitabine among high risk groups can reduce the relative risk for incident HIV infection by over 90%.However,despite…

The Psychosocial Factors that Influencing Antiretroviral Treatment Adherence

Aug 2017 DOI 10.14302/issn.2324-7339.jcrhap-16-1316
Liranso Gebreyohannes SelamuCorresponding author

The socio-cultural context of illness has become a major research area, and it has made significant contributions to our understanding of the socio-cultural dimensions of illness. In this article, we briefly trace the roots of a socio-cultural approach to illness, and we present some of the key find…

Antiretroviral Pre-Exposure Prophylaxis Awareness, Experience and Acceptance among Men who have Sex with Men in Southwest Switzerland

Mar 2016 DOI 10.14302/issn.2324-7339.jcrhap-16-925
K.E.A. DarlingCorresponding author

Objectives Antiretroviral pre-exposure prophylaxis (PrEP) against HIV acquisition has been shown to be safe and effective in populations at risk of HIV acquisition. We examined PrEP awareness, experience and acceptance among men who have sex with men (MSM) in southwest Switzerland. Methods Between 1…

Pattern of Use of Highly Active Antiretroviral Therapy Regimens and Pattern of Occurrence of Adverse Drug Reactions in an Indian Human Immunodeficiency Virus Positive Patients

Jun 2013 DOI 10.14302/issn.2324-7339.jcrhap-12-174
Rajesh RadhakrishnanCorresponding author Radhakrishnan Rajesh M.Pharm, Asst Professor (Senior Grade), Department of Pharmacy Practice, Manipal College of pharmaceutical Sciences, Manipal University, Manipal- 576 104, Karnataka, India.

Background: In India, Human immunodeficiency (HIV) infected patients with highly active antiretroviral therapy (HAART) are at higher risk of developing adverse drug reactions (ADRs). Objectives: The aim of this study was to characterize the pattern of use of HAART, occurrence, incidence, severity an…

When and How Should we be Measuring Adherence to Antiretroviral Therapy in Resource-Limited Settings?

Jun 2013 DOI 10.14302/issn.2324-7339.jcrhap-13-edt.1.2
Denise EvansCorresponding author

This perspective reviews practical approaches to measuring ART adherence in resource‑limited settings. It weighs self‑report, pill counts, pharmacy refill data, and biologic measures, emphasizing feasibility, bias, and programmatic integration to support sustainable HIV care.

Prevalence and Factors Associated with Disclosure of HIV Diagnosis to Infected Children Receiving Antiretroviral Treatment in Public Health Care Facilities in Gauteng, South Africa

Jun 2013 DOI 10.14302/issn.2324-7339.jcrhap-12-74
Sphiwe MadibaCorresponding author

HIV infected children who started antiretroviral therapy (ART) in public health facilities in South Africa have survived to older age and disclosure has become an essential part of their care. Available data on HIV disclosure to children were collected much earlier in the provision of ART in South A…

Evaluation of Direct Cost of Adverse Drug Reactions to Highly Active Antiretroviral Therapy in Indian Human Immunodeficiency Virus Positive Patients

Dec 2012 DOI 10.14302/issn.2324-7339.jcrhap-12-71
Rajesh RadhakrishnanCorresponding author Radhakrishnan Rajesh M.Pharm, Asst Professor (Senior Grade), Department of Pharmacy Practice, Manipal College of pharmaceutical Sciences, Manipal University, Manipal- 576 104, Karnataka, India.

In India, interruptions to highly active antiretroviral therapy (HAART) are due to adverse drug reactions (ADRs) and no reports on the direct cost incurred in the management of ADRs to HAART are available. There is a need to study direct cost incurred with ADRs to HAART to explore the high economic…

Characterization of People Receiving 2-Drug Regimens (2DR) for HIV Management in Italy

Mar 2026 DOI 10.14302/issn.2994-6743.ijstd-26-6060
Pier Francesco AmadeoCorresponding author

Objective To describe the clinical features and real-world treatment of people living with human immunodeficiency virus (PLHIV) using fixed-dose or free combinations of 2-drug regimens (2DR) of antiretroviral therapy (ART). Design Italian retrospective cohort study. Methods Data were extracted from…

A Cross Sectional Analysis of Frailty and Markers of Frailty in Young People Living with HIV/AIDS

Jul 2024 DOI 10.14302/issn.2641-4538.jphi-24-5017
V K SashindranCorresponding author

Background Frailty is an ageing-associated state linked to poor prognostic outcomes. Chronic inflammation due to HIV-infection, AIDS-related infections. and the adverse effects of antiretroviral therapy (ART) all contribute to frailty in people living with HIV/AIDS (PLHA). Frailty has been comprehen…

Invivo Impact of Malaria and HIV Co-Infection on CD4 Cell Count of Infected Patients of Niger Delta Extraction

May 2020 DOI 10.14302/issn.2328-0182.japst-20-3347
Obioma AzuonwuCorresponding author Department of Medical Laboratory Science, Medical Bacteriology / Virology / Parasitology Unit, Rivers State University, Nkpolu – Oroworukwo, Port Harcourt, Rivers State, Nigeria.

The study evaluated the impact of co-infection of malaria parasitaemia, and HIV positive indices on the CD4 cell count of 120 HIV infected subjects, who were already diagnosed and visiting Braithwaite Memorial Specialist Hospital Port Harcourt for routine Medical check-up. Also, a control group of 4…

Perspectives of Health Care Providers Working with HIV Positive Clients on Nutritional Challenges Among People Living with HIV/AIDS in Kigali, Rwanda

Mar 2020 DOI 10.14302/issn.2641-4538.jphi-20-3261
Tafadzwa DzinamariraCorresponding author

Efforts to control the Human Immunodeficiency Virus epidemic in Rwanda have seen remarkable success over the years. Effective antiretroviral therapy has played great role in improving longevity among people living with HIV/AIDS (PLWH). While this is the case, there are various nutritional challenges…

Nucleoside and Nucleotide Reverse Transcriptase Inhibitors Induce Aging by Inhibiting Telomerase Function

Nov 2019 DOI 10.14302/issn.2324-7339.jcrhap-19-3070
Bechan SharmaCorresponding author

The telomeres existing at the end of the eukaryotic chromosome, play an important role in localization, pairing of homologous chromosomes during cell division and synapsis formation, while telomerase is involved in maintenance of the telomere length. The application of antiHIV-1 molecules particular…

Adherence to ART among Pregnant Women Living with HIV/AIDS in Lusaka Urban

Jan 2019 DOI 10.14302/issn.2641-4538.jphi-18-1973
Victoria NthalaCorresponding author

Introduction Adherence to ART is a challenge among pregnant women living with HIV/AIDS. This has an effect on the health of the mother and the unborn child. While studies have been done, it has shown that adherence during pregnancy is a challenge Virological and clinical success depend critically on…

Disability and Health Outcomes – From a Cohort of People on Long Term ART

Aug 2017 DOI 10.14302/issn.2324-7339.jcrhap-17-1430
Hellen MyezwaCorresponding author

HIV and AIDS remains a major health problem in South Africa even after two decades since the introduction of antiretroviral therapy. Long term survival with HIV is associated with new health related issues and a risk of functional limitation/disability. The aim of this study was to assess the impact…

High Rate of Asymptomatic Myocardial Ischemia in HIV Infected Population in Bobo-Dioulasso in Burkina Faso

Nov 2016 DOI 10.14302/issn.2324-7339.jcrhap-16-1271
S. J. B. TougooumaCorresponding author

Introduction The cardiovascular complications have became the 3rd cause of death and the 4th reason for hospitalization of the patients infected by the HIV. The objective of this work was to determine the frequency of asymptomatic myocardial ischemia among patients infected by the HIV receiving anti…

Physical Activity and Risk Factors Screening for Ischaemic Heart Disease in South African Individuals Living with HIV

Feb 2016 DOI 10.14302/issn.2324-7339.jcrhap-13-255
Ronel RoosCorresponding author

People living with HIV (PLWH) are at risk of developing chronic lifestyle diseases such as ischaemic heart disease (IHD). Physical inactivity is a modifiable risk factor for IHD. The level of ambulation physical activity in individuals living with HIV in a South African context is unknown. The aim o…

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