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Apr 2018
Jean-claude PEREZCorresponding author
The global analysis of 3 human genomes of increasing levels of evolution (neanderthal / sapiens build34 of 2003 / sapiens hg38 of 2013) reveals 2 levels of numerical constraints controlling, structuring and optimizing the DNA sequences of these genomes. A global constraint - which we will call "HGO"…
Nov 2017 DOI 10.14302/issn.2638-4469.japb-17-1838
Shridhar JambagiCorresponding author
Strawberry powdery mildew, caused by Podosphaeraaphanis is a major fungal disease that affects strawberry yield and quality. In the model plant species Arabidopsis and the crop plants barley, tomato and pea, the Mildew resistance locus O (MLO) proteins have been found to be required for powdery mild…
Oct 2017 DOI 10.14302/issn.2572-5424.jgm-17-1609
Jean-claude PEREZCorresponding author
DUF1220 proteins regions show the largest Homo-Sapiens lineage-specific increase in copy number of any protein-coding region in the human genome and map principally to 1q21.1. DUF1220 deletions have been associated with microcephaly and macrocephaly, respectively. DUF1220 copy number has been linked…
Sep 2017 DOI 10.14302/issn.2575-7881.jdrr-17-1749
Kiran D. BhilareCorresponding author
Though, directed evolution/In vitro evolution has greatly enhanced the applicability of natural biomolecules, there is still a big void in synthetic biology, which could be filled only when we are able to make novel/synthetic functional biomolecules. Terminal deoxyribonucleotidyl transferase (TdT) i…
Aug 2017 DOI 10.14302/issn.2638-4469.japb-17-1563
Dierk WankeCorresponding author
GAGA-binding proteins in plants are encoded by the BARLEY B-RECOMBINANT / BASIC PENTACYSTEINE (BBR/BPC) family, which can be spilt into several groups on the basis of sequence divergence. The proteins of the different groups share an evolutionary conserved BASIC PENTACYSTEINE (BPC) domain at their v…
Aug 2017 DOI 10.14302/issn.2575-7881.jdrr-17-1701
Wentao XuCorresponding author
Functional nucleic acids are a kind of nucleic acid sequences with special functions, which can specifically bind with the target substances or catalyze the reactions. Many target, including mycotoxins, small RNA, heavy metal ions and DNA segment, can bind to particular selected oligonucleotides, an…
Feb 2017 DOI 10.14302/issn.2381-862X.jwrh-15-848
Anja WittkowskiCorresponding author
Postpartum depression is a common mood disorder following childbirth. Depression occurring at this crucial stage in a child’s life is known to have far reaching and potentially damaging consequences for the mother, the baby and her family. Whilst a number of risk factors have been identified in the…
Jan 2017 DOI 10.14302/issn.2381-862X.jwrh-16-1292
Abdulla Salim Bin GhouthCorresponding author
Objective: A cross-sectional study was designed to collect socio-demographic and obstetric data about female teenagers who have pregnancy and visiting primary health care centers for antenatal care. Subjects and methods: Data were collected by a trained 60 medical students of the 6th level in Hadram…
Dec 2016 DOI 10.14302/issn.2379-8572.joa-16-1369
Stephan KlessingerCorresponding author
The purpose was to discover if medial branch blocks (MBBs) of the cervical spine can be used as a diagnostic tool to identify patients with somatosensory tinnitus. MBBs are a diagnostic tool to confirm the diagnosis facet joint pain in patients with neck pain. It is not known, if MBBs are also suita…
Dec 2016 DOI 10.14302/issn.2476-1710.jdt-16-1260
Ladislav VolicerCorresponding author
Relationship between dementia is very complex and individual. There are some pathogenetic processes that may be common to both conditions: neurotransmitter deficits, vascular changes and beta amyloid deposits. Presence of depression in persons with dementia have serious consequences on progression o…
Oct 2016 DOI 10.14302/issn.2474-9273.jbtm-16-1308
Sara ShabaniCorresponding author
Objectives: While Diabetes Mellitus (DM) affects cognitive functions and the Long Term Memory (LTM), several different strategies are designed to control harmful consequences of DM. This study is investigating whether having Mind Activity (MA) can make any difference in LTM function of individuals w…
Apr 2016 DOI 10.14302/issn.2575-7881.jdrr-15-863
Miguel A. FuertesCorresponding author
It was, previously, reported that the specific pattern of the compositional features of particular human-mouse orthologs defining in human two clusters, named C2 and C5, are present in different clusters in mouse. Since, thus, these orthologs can harbor a significant number of nucleotide differences…
Mar 2016 DOI 10.14302/issn.2470-5020.jnrt-15-800
Lili HuangCorresponding author
Although clinical trials in refractory epilepsy are currently carried out, the field of deep brain stimulation (DBS) in epilepsy is still at its initial stage. Little is known about where, when and how to stimulate and what would be the short and long consequences. Animal studies might provide clini…
Dec 2015 DOI 10.14302/issn.2574-4518.jsdr-14-592
Ann SteeleCorresponding author
Insomnia is highly prevalent and has severe negative consequences. Cognitive Behavioural Therapy for Insomnia (CBT-I) is an evidence-based treatment that is usually delivered individually. Given the high prevalence, accessible one-day CBT-I workshops (each for up to 30 people) were developed to be r…
Jun 2015 DOI 10.14302/issn.2574-4372.jesr-14-607
Michael E. GeuszCorresponding author
Cancer is influenced by the ability of cells to maintain circadian rhythms in molecular and metabolic processes. Disturbance of the underlying circadian timing mechanism in circadian clock cells leads to a higher frequency and more rapid progression of cancer. Cancer stem cells with properties of em…
Mar 2014 DOI 10.14302/issn.2326-0793.jpgr-13-333
Manik C. GhoshCorresponding author
Carbofuran is a broad spectrum pesticide used in agricultural fields and domestic places throughout the world. It is one of the deadly toxic carbamate pesticide that kills the pest by inhibiting the crucial enzyme of nervous system known as acetyl cholinesterase. In the present study, we report how…
Jan 2014 DOI 10.14302/issn.2328-0182.japst-12-183
Supriya D. MahajanCorresponding author
Gold nanorods (GNRs) are plasmonic nanostructures by virtue of their size-dependent optical properties, offer a bionanotechnology platform in areas of bioimaging, drug delivery etc for disease diagnosis, prognosis, and therapy. GNRs are more sensitive to changes in local environments, and offer stro…
Sep 2013 DOI 10.14302/issn.2374-9431.jbd-13-226
Amy Jayne McKnightCorresponding author
The number of individuals with diabetes is increasing worldwide and a large subset of those affected will develop diabetic nephropathy. Diabetic nephropathy is the leading cause of end-stage renal disease, has serious health consequences for affected individuals, and represents a major monetary cost…
Dec 2012 DOI 10.14302/issn.2326-0793.jpgr-12-112
Agnes Ayme-SouthgateCorresponding author
The connecting C-filaments of insect indirect flight muscles have been proposed as one of the elements providing muscle elasticity for the asynchronous muscle physiology of derived insects. Two large modular proteins, kettin/Sallimus and projectin make up these filaments, and for both proteins the N…