Search results for “function”

About 100 results in articles

Open Access Pub publishes peer-reviewed, free-to-read open-access articles. Showing articles matching function — open any to read the full text, or download the PDF or XML.

Functional, Structural and Contextual Analysis of a Variant of Uncertain Clinical Significance in BRCA1: c.5434C->G (p. Pro1812Ala)

Jan 2017 DOI 10.14302/issn.2572-3030.jcgb-16-1307
Rafael MoralesCorresponding author

Interpreting variants of uncertain significance (VUS) for their effect on protein function, and therefore for the risk of developing cancer, has become a challenge in clinical practice for genetic counselling services. The present work combines structural bioinformatics and systems biology based mat…

A Specific Case of Non-Specificity: Longitudinal Effects of Dysfunctional Attitudes on Depressive, Eating Disorder and Aggressive Symptoms in Children and Adolescents 

Jan 2017 DOI 10.14302/issn.2476-1710.jdt-16-1324
Susanne MeiserCorresponding author

An important step in the validation of disorder-specific etiological models is the examination of the predictive specificity of proposed vulnerability factors. It may advance the understanding of the emergence of comorbidity and the identification of at risk-populations for mental disorders. To enha…

The Comparison of Functional Outcomes Between Supraglottic Horizontal Laryngectomy and Supracricoid Partial Laryngectomy

Jan 2017 DOI 10.14302/issn.2379-8572.joa-16-1364
Suat BiliciCorresponding author Istanbul Training and Research Hospital, Otorhinolaryngology Department

Objectives The aim of this study was to compare the functional outcomes (including swallowing, respiration and phonation) of supraglottic horizontal laryngectomy (SGHL) and supracricoid partial laryngectomy (SCPL). Methods The clinical and pathological data were evaluated for 36 previously untreated…

Comparison of Long-Term Memory function in Elderly across Mind Activity and Diabetes Mellitus-Type 2

Oct 2016 DOI 10.14302/issn.2474-9273.jbtm-16-1308
Sara ShabaniCorresponding author

Objectives: While Diabetes Mellitus (DM) affects cognitive functions and the Long Term Memory (LTM), several different strategies are designed to control harmful consequences of DM. This study is investigating whether having Mind Activity (MA) can make any difference in LTM function of individuals w…

Childhood Somatic Complaints: Relationships with Child Emotional Functioning and Parental Factors

Oct 2016 DOI 10.14302/issn.2474-9273.jbtm-16-1173
Francine C. JellesmaCorresponding author

Many schoolchildren experience somatic complaints such as headaches, abdominal pain and fatigue. The aim of the current research is to test the full model of previously found associations between negative affect and somatic complaints in parents and children. Participants were 199 children (aged 8-1…

Fostering Partnerships between Public Health Functions within Health and Social Services Organizations: A Perspective from the Province of Quebec (Canada)

Sep 2016 DOI 10.14302/issn.2474-3585.jpmc-16-1106
Mathieu RoyCorresponding author

Health and social services organizations discriminate too much between core public health functions. Health protection actions, services, and programs are often separate from those concerned with disease prevention and health promotion. In this comment, we advocate for more partnerships between all…

Parental Report of Gender Differences in Sexual Functioning among Adolescents with Down Syndrome: A Jordanian Experience

May 2016 DOI 10.14302/issn.2474-9273.jbtm-15-792
Nevin FW ZakiCorresponding author

Background: Recently, there has been an increased interest in sexuality among teenagers with Down syndrome (DS). Although DS has been well studied in the western continents, its research is relatively scarce in the Arab region. Aims: This is a cross -sectional study to explore the demographic charac…

The Chromosomal and Functional Clustering of Markedly Divergent Human-Mouse Orthologs Run Parallel to their Compositional Features

Apr 2016 DOI 10.14302/issn.2575-7881.jdrr-15-863
Miguel A. FuertesCorresponding author

It was, previously, reported that the specific pattern of the compositional features of particular human-mouse orthologs defining in human two clusters, named C2 and C5, are present in different clusters in mouse. Since, thus, these orthologs can harbor a significant number of nucleotide differences…

Evaluation of the Impact of Clinical, Functional and Social Factors on the Readmission of Patients with Pluripathologies

Apr 2016 DOI 10.14302/issn.2474-7785.jarh-15-699
Valle Coronado-VázquezCorresponding author

Purpose Hospital readmission of patients with pluripathologies is frequent and costly. This study describes the impact of patients’ pluripathologies, functional capacity and social complexity on readmissions during a 12-month period following hospital discharge. Methods A prospective cohort study. M…

Depression and Executive Dysfunction in Young Adults; Implications for Therapy

Mar 2016 DOI 10.14302/issn.2476-1710.jdt-15-825
Deana B DavalosCorresponding author

The prevalence of young adults endorsing depressive symptomatology is thought to peak during late adolescence. While there has been a wealth of research assessing the relationship between decline of the prefrontal cortex and how this process impacts depression and therapy in older adults, very littl…

Influence of Regular Astigmatism on the Human Visual Cortex. A Functional Magnetic Resonance Imaging Study

Oct 2015 DOI 10.14302/issn.2470-0436.jos-14-571
Takuya SHIBACorresponding author

Purpose: To describe a new functional magnetic resonance imaging (fMRI) method for measuring the influence of regular astigmatism, both against-the-rule (ATR) and with-the-rule (WTR), on the human visual cortex. Setting: Department of Ophthalmology, Jikei University School of Medicine, Tokyo, Japan.…

Endothelial Function in Stroke Subtypes Using Endopat Technology

May 2015 DOI 10.14302/issn.2470-5020.jnrt-14-558
Pedro Enrique Jiménez CaballeroCorresponding author

Background. Endothelial function is characterized by the vasodilator capacity of blood vessel smooth muscle cells mediated by nitric oxide. Some studies have shown an inverse association between the endothelial function and the carotid intima-media thickness (IMT). The relationship between endotheli…

Cognitive Functioning in Adults Aging with HIV: A Cross-Sectional Analysis of Cognitive Subtypes and Influential Factors

Feb 2014 DOI 10.14302/issn.2324-7339.jcrhap-13-191
Pariya L. FazeliCorresponding author

Objective: This cross-sectional study examined cognitive subtypes and influential factors in HIV-positive (HIV+) adults. Method: Two-step cluster analysis was conducted on a neurocognitive test battery in a sample (N = 78) of adults and older adults with HIV (Mage = 46.1). Next, cognitive, functiona…

Use of Stem Cell Growth and Differentiation Factors (Scdsf) in Central Vertigo

Oct 2026 DOI 10.14302/issn.2379-8572.joa-26-6454
Giorgia GrappeggiaCorresponding author

The clinical use of SCDSF factors in neuro-degenerative pathologies offers a potential therapeutic opportunity. Our observational study aims to evaluate its efficacy in patients affected by Central Vertigo1. A case series divided into two subgroups, all affected by non-migrainous central vertigo, wa…

From Pelvis to Foot, Part II: A Longitudinal Kinetic Chain Hypothesis for Eversion Ankle Sprains in Athletes

Aug 2026 DOI 10.14302/issn.2694-2283.jsem-26-6342
Gabriel QuinteroCorresponding author

Background Eversion ankle sprains, although less common than inversion injuries, are often associated with greater severity and more complex recovery patterns. Their biomechanical origin remains less clearly understood. Objective To propose a functional, longitudinal kinetic chain model in which ant…

Dietary Intake and Cognitive Developmental Outcomes of Children Below Five Years Living with Special Needs in Kakamega County: A Baseline Survey

Jul 2026 DOI 10.14302/issn.2379-7835.ijn-26-6094
Lucy Amanya MutuliCorresponding author

In early childhood, adequate dietary intake is essential for optimal growth, brain development, and the acquisition of cognitive skills. However, children with special needs often face increased nutritional vulnerability due to feeding difficulties, restricted diets, metabolic anomalies and limited…

Herpes Zoster Ophthalmicus Presenting with Suspected Orbital Myositis Following Recent Recombinant Zoster Vaccination

Jul 2026 DOI 10.14302/issn.2470-0436.jos-26-6357
Muhammad AwanCorresponding author

Herpes zoster ophthalmicus (HZO) is a manifestation of varicella-zoster virus (VZV) reactivation involving the ophthalmic division of the trigeminal nerve, carrying significant risk of vision-threatening complications. Diplopia in HZO is often attributed to cranial nerve palsy, although orbital myos…

Random Forest Classifier for Respiratory Mortality Analytics

Jun 2026 DOI 10.14302/issn.2642-9241.jrd-26-6332
Philip de MeloCorresponding author

Respiratory diseases remain a major contributor to hospital morbidity and mortality worldwide, particularly among elderly patients and individuals with severe pulmonary compromise. Accurate prediction of respiratory mortality is clinically important for triage, resource allocation, ICU utilization,…

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