Search results for “bases”

About 50 results in articles

Open Access Pub publishes peer-reviewed, free-to-read open-access articles. Showing articles matching bases — open any to read the full text, or download the PDF or XML.

Signal Transduction of hCG Induces Decidualization and Uterine Receptivity

Aug 2017 DOI 10.14302/issn.2576-2818.jfb-14-553
L BernardiniCorresponding author

All independent experimental data on epithelial and glandular cells lines of human endometrium support the evidence for a rapid production of eicosanoids from the LH/hCG receptors when exposed to the hCG hormone. Prostaglandins rapidly act on the surrounding endometrial stromal cells throughout the…

Changes in Statistics of Malignant Neoplasms of Central Nervous System Excluding Brain (ICD-10: C70, C72) In the Lower Silesia Region of Poland in the Years 2006-2012

Jun 2017 DOI 10.14302/issn.2470-5020.jnrt-17-1529
Jaroslaw DrobnikCorresponding author

Epidemiological data concerning malignant neoplasms of meninges and central nervous system parts other than brain in Poland are reported to many medical databases run by various institutions and are incongruent with each other which makes their practical interpretation highly difficult. Data on regi…

Supporting Quality Data Systems:  Lessons Learned from Early Implementation of Routine Viral Load Monitoring at a Large Clinic in Lilongwe, Malawi

Mar 2017 DOI 10.14302/issn.2324-7339.jcrhap-17-1468
Jean GibbCorresponding author

Successful viral load programs rely on the presence of data systems and high quality of patient data. Using a cohort of 49 patients at Partners in Hope, a large, urban HIV clinic in Malawi, we performed a quality improvement assessment of a new viral load program with a focus on accuracy of data col…

Bioinformatic Analysis of Coronary Disease Associated SNPs and Genes to Identify Proteins Potentially Involved in the Pathogenesis of Atherosclerosis

Mar 2017 DOI 10.14302/issn.2326-0793.jpgr-17-1447
Timothy D. HowardCorresponding author

Factors that contribute to the onset of atherosclerosis may be elucidated by bioinformatic techniques applied to multiple sources of genomic and proteomic data. The results of genome wide association studies, such as the CardioGramPlusC4D study, expression data, such as that available from expressio…

Obesity in Schizophrenia

May 2016 DOI 10.14302/issn.2574-450X.jom-16-1039
Mary V. SeemanCorresponding author

Over the last three decades, an epidemic of obesity has markedly affected patients suffering from mental illnesses such as schizophrenia. Antipsychotic medications used to treat schizophrenia are considered as major culprits. The aim of this review is to first consider risk factors, to then outline…

High expression of miR-21 in tissue correlated with the poor survival of patients with esophageal cancer: a pilot study using the meta-analysis

Mar 2016 DOI 10.14302/issn.2474-3585.jpmc-15-757
Hong LiuCorresponding author Xijing Hospital of Digestive Diseases, Xijing Hospital, Fourth Military Medical University, Xi'an, 710032,Shaanxi Province, China

Objective: MicroRNAs are involved in the onset, progression and dissemination of esophageal cancer, and they may be useful as prognostic biomarkers. This study aims to evaluate the relation of miR-21 expression and the prognosis of esophageal cancer patients. Methods: In this study, a meta-analysis…

Computational STAT4 rSNP Analysis, Transcriptional Factor Binding Sites and Disease

Feb 2016 DOI 10.14302/issn.2374-9431.jbd-15-890
Norman E. BurokerCorresponding author

Purpose Signal Transducer and Activator of Transcription 4 (STAT4) is important for signaling by interleukins (IL-12 and IL-23) and type 1 interferons and has been found to have several simple nucleotide polymorphisms (SNPs) associated with human disease. STAT4 SNPs were computationally examined wit…

Computational EPAS1 rSNP Analysis, Transcriptional Factor Binding Sites and High Altitude Sickness or Adaptation

Feb 2016 DOI 10.14302/issn.2326-0793.jpgr-15-889
Norman E. BurokerCorresponding author

Purpose The endothetal Per-Arnt-Sim (PAS) domain protein 1 (EPAS1) gene which encodes hypoxia-inducible-factor-2 alpha (HIF2a) is a transcription factor that is involved in the response to hypoxia. EPAS1 has been found to have four (rs56721780, rs6756667, rs7589621, rs1868092) simple nucleotide poly…

Investigations of Molecular Evolutionary Mechanisms in Partially Sequenced Heat Shock Protein70 Homologue-Coding Gene of Olive Leaf Yellowing-Associated Virus Isolates from Tunisia

Feb 2016 DOI 10.14302/issn.2575-7881.jdrr-15-849
Moncef BOULILACorresponding author

Reverse Transcription Polymerase Chain Reaction (RT-PCR) using new designed primers pair for Heat Shock Protein70 homologue (HSP70h) of Olive leaf yellowing-associated virus revealed 667 amplified product of 10 olive accessions collected from various olive-growing regions in Tunisia. Amplicons were…

A Systematic Review of the use of Bupropion for Hypoactive Sexual Desire Disorder in Premenopausal Women

Jun 2015 DOI 10.14302/issn.2381-862X.jwrh-14-546
David M. HaasCorresponding author

Objective: To assess the efficacy of bupropion therapy for hypoactive sexual desire disorder (HSDD) in women. Methods: A systematic review was performed utilizing the standard databases. Data were abstracted for study quality, characteristics, and outcomes. Due to the small number of studies and lac…

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