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Sep 2020 DOI 10.14302/issn.2470-0436.jos-20-3400
Eman Abo TalebCorresponding author
Aim To compare the efficacy of combined anti-VGEF (IVB) with steroids versus pure anti-VEGF for the treatment of macular edema secondary to retinal vein occlusion (RVO). Methods In this prospective study, 51 eyes were randomized into 2 groups according to treatment of clinically identified macular e…
Sep 2019 DOI 10.14302/issn.2470-0436.jos-19-2829
Eman Abo TalebCorresponding author
Purpose To study outcome and spectral domain optical coherence tomography (SD-OCT) macular findings in patients who underwent surgery for spared macula giant retinal tear (GRT) retinal detachment. Methods a retrospective study of 12 patients with spared macula giant retinal tear (GRT) retinal detach…
Aug 2017 DOI 10.14302/issn.2470-0436.jos-17-1721
Damien C. RodgerCorresponding author
A 57-year-old Hispanic female presented with 3 days of blurry vision in the left eye. Eight years prior, she had a branch retinal artery occlusion in the right eye and a hematologic work-up revealed a 4G/4G polymorphism in plasminogen activator inhibitor-1. With the current episode, she was found to…
May 2017 DOI 10.14302/issn.2470-0436.jos-17-1453
Jie ZhangCorresponding author
Purpose: High intraocular pressure (IOP) is known to result in retinal ganglion cell (RGC) loss, both with chronically raised intraocular pressure (such as with glaucoma) and with acute raises in pressure (due to injury or acute angle closure). Because IOP is often raised during ocular surgery, the…
Apr 2016 DOI 10.14302/issn.2470-0436.jos-15-710
Claudio CampaCorresponding author
Idiopathic macular telangiectasia type 2 is a rare retinal condition usually characterized by parafoveal telangiectatic vessels, hyperplastic pigment plaques and seldom a full thickness macular hole or a retinal neovascularisation. Herein we describe an atypical presentation of this disease. Methods…
Mar 2016 DOI 10.14302/issn.2470-0436.jos-15-739
Vijay P. SarthyCorresponding author
Ciliary neurotrophic factor (CNTF) is a well-tested, neuroprotective agent that has been shown to retard photoreceptor degeneration in several animal models of retinitis pigmentosa. The molecular mechanisms underlying CNTF-mediated neuroprotection are currently not understood. CNTF could act directl…
Jun 2015 DOI 10.14302/issn.2470-0436.jos-14-528
Sanjay SrinivasanCorresponding author
Ophthalmology and Visual Sciences, Khoo Teck Puat Hospital, Singapore
A previously healthy 25 year old Chinese male presented with left eye blurring of vision and was diagnosed to have left eye branch retinal vein occlusion. Initial blood investigations and thrombophilia screen were negative. The patient subsequently improved with observation and conservative manageme…
May 2015 DOI 10.14302/issn.2470-0436.jos-14-527
Srinivasan SanjayCorresponding author
A 66 year old Chinese male with a medical history of hypertension, diabetes mellitus and hepatitis B carrier was diagnosed with hepatocellular carcinoma in 2009. He underwent treatment with selective internal radiation spheres and sorafenib, and multiple cycles of chemotherapeutic agents such as bev…
Nov 2025 DOI 10.14302/issn.2470-0436.jos-25-5503
Mark H. NelsonCorresponding author
Purpose Create a new diagnostic and therapeutic framework for patients with Exudative Age-Related Macular Degeneration (ARMD) and choroid imaging biomarkers of non-neovascular choroidal pathology who have persistent neovascular exudation during the course of monotherapeutic interventions. Methods Re…
Aug 2024 DOI 10.14302/issn.2470-0436.jos-24-5162
João Alves AmbrósioCorresponding author
Introduction Cystoid macular edema (CME) is a sight-threatening condition caused by fluid accumulation in the macula due to blood-retinal barrier disruption. Various factors, including drug reactions, can lead to retinal fluid leakage. Leflunomide, a disease-modifying anti-rheumatic drug, marked sig…
Nov 2023 DOI 10.14302/issn.2470-0436.jos-23-4814
Joao Alves-AmbrósioCorresponding author
A 40-year-old male presented with visual impairment in the right eye (OD). He had undergone a pars plana vitrectomy for retinal detachment in the OD three years prior. Biomicroscopic examination revealed significant hyperemia, rubeosis iridis, anterior subluxation of the intraocular lens (IOL), and…
Jul 2019 DOI 10.14302/issn.2470-0436.jos-19-2904
Ronald Y. TiuCorresponding author
This case series presents 2 patients (67 and 58 year old females) with resolving vitreous hemorrhage in the setting of diabetic retinopathy. Both patients had around 50% of the retina still visible and the hemorrhage was confined at the posterior vitreous cavity near the retina, hence, a partial pan…
Apr 2019 DOI 10.14302/issn.2470-0436.jos-19-2480
Eman Abo TalebCorresponding author
Purpose To describe spectral domain optical coherence tomography (SD-OCT) and enhanced depth image OCT (EDI-OCT) findings of multifocal serpiginoid choroditis (MSC) , including affected layer of retinal involvement, changes at the vitreoretinal interface, and response to therapy. Methods A retrospec…
Aug 2018 DOI 10.14302/issn-2470-0436.jos-18-2222
Eleonore B. IgubanCorresponding author
Objective: The aim of the present study is to determine the efficiency of third year ophthalmology residents from a tertiary hospital in performing preliminary retinal examination to identify eyes at risk retinopathy of prematurity on the basis of retinal fundus findings up to International Classifi…
Jun 2017 DOI 10.14302/issn.2470-0436.jos-17-1442
Ozkan KocamisCorresponding author
Objective: Determining the effects on macular ganglion cell layer thickness in patients using isotretinoin by utilization of optical coherence tomography. Material and Methods: Sixty eyes of 30 patients using isotretinoin and 60 eyes of 30 control group patients in the same age range were included i…
Apr 2017 DOI 10.14302/issn.2470-0436.jos-17-988
Ying-Ling ChenCorresponding author
Photorefraction (PR) methods have beenwidely used for pediatric vision screening since the 1980’s. While PR is easy to implement, the accuracy of refractive error measurements in humans has been unsatisfactory, largely due to the variations of intraocular scattering, the retinal reflectance, and pup…
Apr 2016 DOI 10.14302/issn.2470-0436.jos-15-763
Karim El-AssalCorresponding author
Background: Optic nerve head drusen are acellular hyaline deposits located anterior to the lamina cribrosa, frequently associated with visual field defects. Sometimes rapid worsening of vision may occur due to complications such as acute vascular events, choroidal neovascularization, or serous macul…